| Transcribed genes |
| Gene | Score | GO annotation |
| THOC5 | 8 |
BP MF CC |
| biological_process | - RNA splicing
- cell differentiation
- intronless viral mRNA export from host nucleus
- mRNA export from nucleus
more... - mRNA processing
- monocyte differentiation
- negative regulation of macrophage differentiation
- primitive hemopoiesis
- transport
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|
| | | molecular_function | - RNA binding
- protein binding
|
| |
| RECK | 8 |
BP MF CC |
| biological_process | - negative regulation of endopeptidase activity
|
| | cellular_component | - anchored to membrane
- membrane fraction
- peripheral to membrane of membrane fraction
- plasma membrane
more...
|
| | molecular_function | - endopeptidase inhibitor activity
- metalloendopeptidase inhibitor activity
- serine-type endopeptidase inhibitor activity
|
| |
| CCNO | 8 |
BP MF CC |
| | | molecular_function | - protein kinase binding
- uracil DNA N-glycosylase activity
|
| |
| SPSB1 | 8 |
BP MF CC |
| biological_process | - intracellular signal transduction
|
| | | |
| CREBBP | 8 |
BP MF CC |
| biological_process | - N-terminal peptidyl-lysine acetylation
- cell proliferation
- cellular lipid metabolic process
- gene expression
more... - histone acetylation
- homeostatic process
- innate immune response
- interspecies interaction between organisms
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription, DNA-dependent
- protein complex assembly
- regulation of S phase
- regulation of transcription, DNA-dependent
- response to hypoxia
- signal transduction
- transcription, DNA-dependent
less...
|
| | cellular_component | - cytoplasm
- histone acetyltransferase complex
- nuclear body
- nucleoplasm
more... - nucleus
less...
|
| | molecular_function | - MyoD binding
- SMAD binding
- acetyltransferase activity
- histone acetyltransferase activity
more... - metal ion binding
- p53 binding
- peroxisome proliferator activated receptor binding
- protein binding
- sequence-specific DNA binding transcription factor activity
- signal transducer activity
- transcription coactivator activity
- transcription factor binding
- transferase activity
- zinc ion binding
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|
| |
| ZC3H15 | 8 |
BP MF CC |
| biological_process | - cytokine-mediated signaling pathway
|
| | cellular_component | - cytoplasm
- nucleolus
- nucleus
- plasma membrane
more...
|
| | molecular_function | - metal ion binding
- nucleic acid binding
- zinc ion binding
|
| |
| CCDC117 | 8 |
BP MF CC |
|
| ATP13A3 | 8 |
BP MF CC |
| biological_process | - ATP biosynthetic process
- cation transport
|
| | cellular_component | - integral to membrane
- membrane
|
| | molecular_function | - ATP binding
- ATPase activity
- ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
- hydrolase activity
more... - hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
- metal ion binding
- nucleotide binding
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|
| |
| DNM2 | 8 |
BP MF CC |
| biological_process | - G2/M transition of mitotic cell cycle
- GTP catabolic process
- cellular membrane organization
- endocytosis
more... - positive regulation of apoptosis
- positive regulation of transcription, DNA-dependent
- post-Golgi vesicle-mediated transport
- receptor internalization
- regulation of transcription, DNA-dependent
- signal transduction
- synaptic vesicle transport
- transferrin transport
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|
| | cellular_component | - Golgi membrane
- cell junction
- clathrin-coated endocytic vesicle
- cytoplasm
more... - cytoskeleton
- cytosol
- microtubule
- nucleus
- plasma membrane
- postsynaptic density
- postsynaptic membrane
- synapse
less...
|
| | |
| COG3 | 8 |
BP MF CC |
| biological_process | - ER to Golgi vesicle-mediated transport
- intra-Golgi vesicle-mediated transport
- intracellular protein transport
- protein glycosylation
more... - protein localization to organelle
- protein stabilization
- protein transport
- retrograde vesicle-mediated transport, Golgi to ER
less...
|
| | cellular_component | - Golgi apparatus
- Golgi cisterna membrane
- Golgi transport complex
- cis-Golgi network
more... - membrane
less...
|
| | molecular_function | - protein binding
- protein transporter activity
|
| |
| LSR | 8 |
BP MF CC |
| biological_process | - embryo development
- liver development
- regulation of lipid metabolic process
|
| | | |
| PPM1K | 8 |
BP MF CC |
| biological_process | - protein dephosphorylation
|
| | cellular_component | - mitochondrial matrix
- mitochondrion
- protein serine/threonine phosphatase complex
|
| | molecular_function | - hydrolase activity
- metal ion binding
- protein serine/threonine phosphatase activity
|
| |
| NRAS | 8 |
BP MF CC |
| biological_process | - MAPKKK cascade
- Ras protein signal transduction
- actin cytoskeleton organization
- activation of MAPKK activity
more... - axon guidance
- blood coagulation
- epidermal growth factor receptor signaling pathway
- insulin receptor signaling pathway
- leukocyte migration
- nerve growth factor receptor signaling pathway
- positive regulation of Rac protein signal transduction
- positive regulation of cell proliferation
- regulation of long-term neuronal synaptic plasticity
- regulation of synaptic transmission, GABAergic
- signal transduction
- small GTPase mediated signal transduction
- striated muscle cell differentiation
- visual learning
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|
| | cellular_component | - Golgi apparatus
- Golgi membrane
- membrane fraction
- plasma membrane
more...
|
| | molecular_function | - GTP binding
- GTPase activity
- Ral guanyl-nucleotide exchange factor activity
- nucleotide binding
more...
|
| |
| TFAP2C | 8 |
BP MF CC |
| biological_process | - cell-cell signaling
- cerebral cortex development
- dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
- epithelial cell proliferation involved in mammary gland duct elongation
more... - forebrain neuron fate commitment
- germ-line stem cell maintenance
- hair follicle development
- keratinocyte development
- male gonad development
- negative regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription from RNA polymerase II promoter
- regulation of epidermis development
- regulation of transcription from RNA polymerase II promoter
- sebaceous gland development
- skin development
- somatic stem cell maintenance
- transcription, DNA-dependent
- trophectodermal cell differentiation
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|
| | | molecular_function | - DNA binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
- RNA polymerase II distal enhancer sequence-specific DNA binding
more... - protein binding
- protein dimerization activity
- sequence-specific DNA binding RNA polymerase II transcription factor activity
- sequence-specific DNA binding transcription factor activity
less...
|
| |
| PNKD | 8 |
BP MF CC |
| | cellular_component | - cytoplasm
- membrane
- mitochondrion
- nucleus
more...
|
| | molecular_function | - hydrolase activity
- hydroxyacylglutathione hydrolase activity
- metal ion binding
- zinc ion binding
more...
|
| |
| EPHA2 | 8 |
BP MF CC |
| biological_process | - activation of Rac GTPase activity
- apoptosis
- axial mesoderm formation
- blood vessel development
more... - bone remodeling
- branching involved in mammary gland duct morphogenesis
- cell chemotaxis
- ephrin receptor signaling pathway
- keratinocyte differentiation
- lens fiber cell morphogenesis
- mammary gland epithelial cell proliferation
- multicellular organismal development
- negative regulation of protein kinase B signaling cascade
- neural tube development
- neuron differentiation
- notochord cell development
- notochord formation
- osteoblast differentiation
- osteoclast differentiation
- positive regulation of establishment of protein localization in plasma membrane
- protein kinase B signaling cascade
- regulation of ERK1 and ERK2 cascade
- regulation of angiogenesis
- regulation of blood vessel endothelial cell migration
- regulation of cell adhesion mediated by integrin
- regulation of lamellipodium assembly
- response to growth factor stimulus
- skeletal system development
- tail morphogenesis
- vasculogenesis
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|
| | | |
| FDX1L | 8 |
BP MF CC |
| biological_process | - electron transport chain
- transport
|
| | cellular_component | - mitochondrial matrix
- mitochondrion
|
| | molecular_function | - 2 iron, 2 sulfur cluster binding
- electron carrier activity
- metal ion binding
|
| |
| MPV17 | 8 |
BP MF CC |
| | cellular_component | - integral to membrane
- integral to peroxisomal membrane
- membrane
- mitochondrial inner membrane
more... - mitochondrion
less...
|
| | |
| UAP1L1 | 8 |
BP MF CC |
| | | molecular_function | - nucleotidyltransferase activity
- transferase activity
|
| |
| SLC25A33 | 8 |
BP MF CC |
| | cellular_component | - integral to membrane
- membrane
- mitochondrial inner membrane
- mitochondrion
more...
|
| | |
| NMT1 | 8 |
BP MF CC |
| | cellular_component | - actin cytoskeleton
- cell junction
- cytoplasm
- cytosol
more... - plasma membrane
less...
|
| | molecular_function | - catalytic activity
- glycylpeptide N-tetradecanoyltransferase activity
- transferase activity
- transferase activity, transferring acyl groups
more...
|
| |
| LRRC23 | 8 |
BP MF CC |
|
| MTCH2 | 8 |
BP MF CC |
| | cellular_component | - integral to membrane
- membrane
- mitochondrial inner membrane
- mitochondrion
more...
|
| | |
| MYL6B | 8 |
BP MF CC |
| biological_process | - muscle contraction
- muscle filament sliding
- skeletal muscle tissue development
|
| | cellular_component | - cytosol
- muscle myosin complex
- myosin complex
- unconventional myosin complex
more...
|
| | molecular_function | - calcium ion binding
- motor activity
- protein binding
- structural constituent of muscle
more...
|
| |
| ANGEL2 | 8 |
BP MF CC |
|
| TMEM179B | 8 |
BP MF CC |
| | cellular_component | - integral to membrane
- membrane
|
| | |
| PDXP | 8 |
BP MF CC |
|
| MED12 | 8 |
BP MF CC |
| biological_process | - androgen receptor signaling pathway
- gene expression
- negative regulation of Wnt receptor signaling pathway
- positive regulation of transcription from RNA polymerase II promoter
more... - positive regulation of transcription, DNA-dependent
- regulation of transcription from RNA polymerase II promoter
- steroid hormone receptor signaling pathway
- transcription initiation from RNA polymerase II promoter
less...
|
| | cellular_component | - mediator complex
- nucleoplasm
- nucleus
|
| | molecular_function | - RNA polymerase II transcription cofactor activity
- beta-catenin binding
- ligand-dependent nuclear receptor transcription coactivator activity
- protein C-terminus binding
more... - protein domain specific binding
- receptor activity
- thyroid hormone receptor binding
- transcription coactivator activity
- transcription cofactor activity
- vitamin D receptor binding
less...
|
| |
| MOXD1 | 8 |
BP MF CC |
| biological_process | - catecholamine metabolic process
- cellular process
- oxidation-reduction process
|
| | cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- integral to membrane
- membrane
more...
|
| | molecular_function | - copper ion binding
- dopamine beta-monooxygenase activity
- metal ion binding
- monooxygenase activity
more...
|
| |
| PPA1 | 8 |
BP MF CC |
| biological_process | - diphosphate metabolic process
- gene expression
- phosphate-containing compound metabolic process
- tRNA aminoacylation for protein translation
more...
|
| | | molecular_function | - hydrolase activity
- inorganic diphosphatase activity
- magnesium ion binding
|
| |
| ZNF675 | 8 |
BP MF CC |
| biological_process | - I-kappaB kinase/NF-kappaB cascade
- bone resorption
- cytokine-mediated signaling pathway
- negative regulation of JNK cascade
more... - negative regulation of JUN kinase activity
- negative regulation of NF-kappaB transcription factor activity
- negative regulation of interleukin-1-mediated signaling pathway
- negative regulation of osteoclast differentiation
- negative regulation of transcription from RNA polymerase II promoter
- negative regulation of transcription regulatory region DNA binding
- negative regulation of tumor necrosis factor-mediated signaling pathway
- regulation of transcription, DNA-dependent
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|
| | cellular_component | - intracellular
- nucleus
- perinuclear region of cytoplasm
|
| | molecular_function | - DNA binding
- metal ion binding
- protein binding
- ubiquitin protein ligase binding
more... - zinc ion binding
less...
|
| |
| IFRD1 | 8 |
BP MF CC |
| biological_process | - adult somatic muscle development
- multicellular organismal development
- muscle cell differentiation
- myoblast cell fate determination
more...
|
| | | |
| AGGF1 | 8 |
BP MF CC |
| | cellular_component | - cytoplasm
- extracellular region
- intracellular
- perinuclear region of cytoplasm
more...
|
| | molecular_function | - eukaryotic cell surface binding
- nucleic acid binding
- protein binding
|
| |
| DPF1 | 8 |
BP MF CC |
| biological_process | - induction of apoptosis
- nervous system development
- regulation of transcription, DNA-dependent
|
| | cellular_component | - cytoplasm
- intracellular
- nBAF complex
- nucleus
more...
|
| | molecular_function | - metal ion binding
- nucleic acid binding
- zinc ion binding
|
| |
| BDP1 | 8 |
BP MF CC |
| biological_process | - regulation of transcription, DNA-dependent
- transcription from RNA polymerase III promoter
|
| | | |
| RAPH1 | 8 |
BP MF CC |
| biological_process | - cell-matrix adhesion
- signal transduction
|
| | cellular_component | - cytoplasm
- cytoskeleton
- filopodium
- lamellipodium
more... - nucleus
- plasma membrane
less...
|
| | |
| TRIM6 | 8 |
BP MF CC |
| | | molecular_function | - metal ion binding
- molecular_function
- zinc ion binding
|
| |
| CLN5 | 8 |
BP MF CC |
|
| RDH11 | 8 |
BP MF CC |
| biological_process | - retinoid metabolic process
- retinol metabolic process
- steroid metabolic process
|
| | cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- integral to membrane
- intracellular
more... - membrane
less...
|
| | molecular_function | - NADP-retinol dehydrogenase activity
- binding
- oxidoreductase activity
- retinol dehydrogenase activity
more...
|
| |
| TSR1 | 8 |
BP MF CC |
|
| EHMT2 | 8 |
BP MF CC |
| biological_process | - DNA methylation
- chromatin modification
- fertilization
- histone H3-K27 methylation
more... - histone H3-K9 methylation
- negative regulation of transcription from RNA polymerase II promoter
- organ growth
- pachytene
- peptidyl-lysine dimethylation
- spermatid development
- synaptonemal complex assembly
less...
|
| | | molecular_function | - histone methyltransferase activity (H3-K27 specific)
- histone methyltransferase activity (H3-K9 specific)
- histone-lysine N-methyltransferase activity
- metal ion binding
more... - methyltransferase activity
- p53 binding
- protein binding
- protein-lysine N-methyltransferase activity
- transferase activity
- zinc ion binding
less...
|
| |
| CEPT1 | 8 |
BP MF CC |
| biological_process | - lipid metabolic process
- phospholipid biosynthetic process
|
| | cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- integral to membrane
- membrane
more... - nuclear membrane
- nucleus
less...
|
| | molecular_function | - diacylglycerol cholinephosphotransferase activity
- ethanolaminephosphotransferase activity
- metal ion binding
- phosphotransferase activity, for other substituted phosphate groups
more... - transferase activity
less...
|
| |
| N4BP1 | 8 |
BP MF CC |
| biological_process | - negative regulation of proteasomal ubiquitin-dependent protein catabolic process
- negative regulation of protein ubiquitination
|
| | | |
| ZMAT2 | 8 |
BP MF CC |
| | | molecular_function | - DNA binding
- metal ion binding
- zinc ion binding
|
| |
| SNRPC | 8 |
BP MF CC |
| biological_process | - nuclear mRNA splicing, via spliceosome
- spliceosomal snRNP assembly
|
| | cellular_component | - Cajal body
- U1 snRNP
- nucleus
- ribonucleoprotein complex
more...
|
| | |
| PPAP2A | 8 |
BP MF CC |
| biological_process | - activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
- androgen receptor signaling pathway
- germ cell migration
- lipid metabolic process
more... - negative regulation of cell proliferation
- phospholipid dephosphorylation
- regulation of lipid metabolic process
- sphingolipid metabolic process
- steroid hormone receptor signaling pathway
less...
|
| | cellular_component | - integral to plasma membrane
- membrane fraction
- plasma membrane
|
| | molecular_function | - hydrolase activity
- phosphatidate phosphatase activity
|
| |
| WAC | 8 |
BP MF CC |
| biological_process | - cell cycle checkpoint
- chromatin modification
- histone H2B conserved C-terminal lysine ubiquitination
- histone monoubiquitination
more... - positive regulation of transcription, DNA-dependent
- response to DNA damage stimulus
less...
|
| | cellular_component | - nuclear speck
- nucleus
- spliceosomal complex
|
| | molecular_function | - RNA polymerase II core binding
- chromatin binding
- protein binding
|
| |
| DHRS11 | 8 |
BP MF CC |
| | | molecular_function | - binding
- oxidoreductase activity
|
| |
| RELA | 8 |
BP MF CC |
| biological_process | - MyD88-dependent toll-like receptor signaling pathway
- MyD88-independent toll-like receptor signaling pathway
- T cell receptor signaling pathway
- Toll signaling pathway
more... - acetaldehyde metabolic process
- aging
- anti-apoptosis
- cellular defense response
- cellular response to lipopolysaccharide
- cytokine-mediated signaling pathway
- defense response
- defense response to virus
- hair follicle development
- inflammatory response
- innate immune response
- interspecies interaction between organisms
- liver development
- membrane protein intracellular domain proteolysis
- negative regulation of apoptosis
- negative regulation of insulin receptor signaling pathway
- negative regulation of protein catabolic process
- negative regulation of transcription, DNA-dependent
- nerve growth factor receptor signaling pathway
- nucleotide-binding oligomerization domain containing 2 signaling pathway
- organ morphogenesis
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- positive regulation of NF-kappaB transcription factor activity
- positive regulation of Schwann cell differentiation
- positive regulation of cell proliferation
- positive regulation of chondrocyte differentiation
- positive regulation of interleukin-12 biosynthetic process
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription, DNA-dependent
- regulation of inflammatory response
- response to UV-B
- response to amino acid stimulus
- response to bacterium
- response to cAMP
- response to cobalamin
- response to cytokine stimulus
- response to drug
- response to hydrogen peroxide
- response to inorganic substance
- response to insulin stimulus
- response to interleukin-1
- response to mechanical stimulus
- response to morphine
- response to muramyl dipeptide
- response to organic cyclic compound
- response to organic substance
- response to progesterone stimulus
- toll-like receptor 1 signaling pathway
- toll-like receptor 2 signaling pathway
- toll-like receptor 3 signaling pathway
- toll-like receptor 4 signaling pathway
- toll-like receptor signaling pathway
- transcription, DNA-dependent
less...
|
| | | molecular_function | - DNA binding
- NF-kappaB binding
- activating transcription factor binding
- ankyrin repeat binding
more... - chromatin binding
- identical protein binding
- phosphate ion binding
- protein N-terminus binding
- protein binding
- protein kinase binding
- repressing transcription factor binding
- sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
- sequence-specific distal enhancer binding RNA polymerase II transcription factor activity
- transcription factor binding
- transcription regulatory region DNA binding
- ubiquitin protein ligase binding
less...
|
| |
| GPD1L | 8 |
BP MF CC |
| biological_process | - carbohydrate metabolic process
- glycerol-3-phosphate catabolic process
- oxidation-reduction process
|
| | cellular_component | - cytoplasm
- glycerol-3-phosphate dehydrogenase complex
|
| | molecular_function | - NAD binding
- binding
- glycerol-3-phosphate dehydrogenase [NAD+] activity
- protein homodimerization activity
more...
|
| |
| CNN3 | 8 |
BP MF CC |
| biological_process | - actomyosin structure organization
- smooth muscle contraction
|
| | | molecular_function | - actin binding
- calmodulin binding
- tropomyosin binding
- troponin C binding
more...
|
| |
| NDUFA9 | 8 |
BP MF CC |
| | | molecular_function | - 3-beta-hydroxy-delta5-steroid dehydrogenase activity
- NADH dehydrogenase (ubiquinone) activity
- NADH dehydrogenase activity
- binding
more... - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
less...
|
| |
| C6orf1 | 8 |
BP MF CC |
|
| IDH3A | 8 |
BP MF CC |
| biological_process | - 2-oxoglutarate metabolic process
- NADH metabolic process
- carbohydrate metabolic process
- isocitrate metabolic process
more... - tricarboxylic acid cycle
less...
|
| | cellular_component | - mitochondrial matrix
- mitochondrion
|
| | molecular_function | - NAD binding
- isocitrate dehydrogenase (NAD+) activity
- magnesium ion binding
- oxidoreductase activity
more... - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
less...
|
| |
| TMEM147 | 8 |
BP MF CC |
| | cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- integral to membrane
- membrane
more...
|
| | |
| DNAJB14 | 8 |
BP MF CC |
| | cellular_component | - integral to membrane
- membrane
|
| | molecular_function | - heat shock protein binding
- unfolded protein binding
|
| |
| MAGI3 | 8 |
BP MF CC |
| biological_process | - apoptosis
- interspecies interaction between organisms
- intracellular signal transduction
|
| | | molecular_function | - ATP binding
- guanylate kinase activity
- nucleotide binding
- protein binding
more...
|
| |
| XPO1 | 8 |
BP MF CC |
| biological_process | - M phase of mitotic cell cycle
- RNA metabolic process
- interspecies interaction between organisms
- intracellular protein transport
more... - mRNA metabolic process
- mRNA transport
- mitotic cell cycle
- mitotic prometaphase
- negative regulation of transcription from RNA polymerase II promoter
- protein localization to nucleus
- regulation of centrosome duplication
- regulation of protein catabolic process
- regulation of protein export from nucleus
- response to drug
- viral genome transport in host cell
- viral infectious cycle
- viral reproduction
less...
|
| | | |
| ACAT2 | 8 |
BP MF CC |
| | cellular_component | - cytoplasm
- mitochondrion
- nucleolus
- nucleus
more...
|
| | molecular_function | - acetyl-CoA C-acetyltransferase activity
- transferase activity
- transferase activity, transferring acyl groups other than amino-acyl groups
|
| |
| Magmas | 8 |
BP MF CC |
|
| KATNB1 | 8 |
BP MF CC |
| biological_process | - cell cycle
- cell division
- microtubule severing
- mitosis
more... - negative regulation of microtubule depolymerization
- positive regulation of cell death
- positive regulation of microtubule depolymerization
- positive regulation of neuron projection development
- protein targeting
less...
|
| | | molecular_function | - dynein binding
- microtubule binding
- microtubule-severing ATPase activity
- protein heterodimerization activity
more...
|
| |
| C2orf34 | 8 |
BP MF CC |
|
| HMGA2 | 8 |
BP MF CC |
| biological_process | - DNA damage response, detection of DNA damage
- base-excision repair
- cell cycle
- cell division
more... - chondrocyte differentiation
- chondrocyte proliferation
- chromatin organization
- chromosome breakage
- chromosome condensation
- endodermal cell differentiation
- epithelial to mesenchymal transition
- fat cell differentiation
- heterochromatin formation
- histone H2A-S139 phosphorylation
- mesenchymal cell differentiation
- mesodermal cell differentiation
- mesodermal-endodermal cell signaling
- mitosis
- mitotic cell cycle G2/M transition DNA damage checkpoint
- multicellular organismal development
- negative regulation by host of viral transcription
- negative regulation of DNA binding
- negative regulation of apoptosis
- negative regulation of double-strand break repair via nonhomologous end joining
- negative regulation of retroviral genome replication
- negative regulation of transcription from RNA polymerase II promoter
- negative regulation of transcription, DNA-dependent
- oncogene-induced senescence
- positive regulation of apoptosis
- positive regulation of cell cycle arrest
- positive regulation of cellular response to X-ray
- positive regulation of cellular senescence
- positive regulation of gene expression
- positive regulation of response to DNA damage stimulus
- positive regulation of stem cell proliferation
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription regulatory region DNA binding
- positive regulation of transcription, DNA-dependent
- regulation of cell cycle process
- regulation of cellular response to drug
- regulation of growth
- regulation of stem cell maintenance
- regulation of transcription, DNA-dependent
- response to virus
- senescence-associated heterochromatin focus formation
- stem cell differentiation
less...
|
| | | molecular_function | - 5'-deoxyribose-5-phosphate lyase activity
- AT DNA binding
- C2H2 zinc finger domain binding
- DNA bending activity
more... - DNA binding
- DNA-(apurinic or apyrimidinic site) lyase activity
- DNA-dependent protein kinase activity
- MH1 domain binding
- MH2 domain binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
- SMAD binding
- cAMP response element binding
- core promoter binding
- nucleic acid binding transcription factor activity
- nucleosomal DNA binding
- protein binding
- protein binding transcription factor activity
- regulatory region DNA binding
- transcription factor binding
less...
|
| |
| TGIF2 | 8 |
BP MF CC |
| biological_process | - positive regulation of neuron differentiation
- regulation of transcription, DNA-dependent
- retina development in camera-type eye
- transcription, DNA-dependent
more...
|
| | | molecular_function | - sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
|
| |
| ATP5B | 8 |
BP MF CC |
| biological_process | - ADP biosynthetic process
- ATP biosynthetic process
- ATP catabolic process
- ATP hydrolysis coupled proton transport
more... - ATP metabolic process
- ATP synthesis coupled proton transport
- angiogenesis
- generation of precursor metabolites and energy
- ion transport
- lipid metabolic process
- mitochondrial ATP synthesis coupled proton transport
- negative regulation of cell adhesion involved in substrate-bound cell migration
- proton transport
- receptor-mediated endocytosis
- regulation of intracellular pH
- respiratory electron transport chain
- transport
less...
|
| | cellular_component | - cell surface
- mitochondrial matrix
- mitochondrial membrane
- mitochondrial nucleoid
more... - mitochondrial proton-transporting ATP synthase complex
- mitochondrial proton-transporting ATP synthase, catalytic core
- mitochondrion
- plasma membrane
- proton-transporting ATP synthase complex, catalytic core F(1)
- proton-transporting two-sector ATPase complex
less...
|
| | molecular_function | - ATP binding
- ATPase activity
- MHC class I protein binding
- calcium ion binding
more... - eukaryotic cell surface binding
- hydrogen ion transporting ATP synthase activity, rotational mechanism
- hydrogen-exporting ATPase activity, phosphorylative mechanism
- hydrolase activity
- hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
- lipoprotein particle receptor activity
- nucleoside-triphosphatase activity
- nucleotide binding
- protein binding
- proton-transporting ATPase activity, rotational mechanism
- transmembrane transporter activity
- transporter activity
less...
|
| |
| ZCCHC11 | 8 |
BP MF CC |
| biological_process | - RNA 3'-end processing
- cytokine production
- gene silencing by RNA
- histone mRNA catabolic process
more... - miRNA catabolic process
- miRNA metabolic process
- negative regulation of NF-kappaB transcription factor activity
- pre-miRNA processing
- regulation of lipopolysaccharide-mediated signaling pathway
- stem cell maintenance
less...
|
| | cellular_component | - cytoplasm
- nucleolus
- nucleus
|
| | |
| IFT88 | 8 |
BP MF CC |
| biological_process | - anterior/posterior pattern specification
- brain development
- cardiac septum morphogenesis
- cell projection organization
more... - cilium morphogenesis
- determination of left/right symmetry
- dorsal/ventral pattern formation
- embryonic digit morphogenesis
- embryonic organ development
- forebrain morphogenesis
- in utero embryonic development
- lung vasculature development
- nervous system development
- organ morphogenesis
- positive regulation of proteolysis
- protein processing
- regulation of odontogenesis of dentine-containing tooth
- smoothened signaling pathway
- telencephalon development
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| | cellular_component | - axoneme
- centriole
- cilium
- cytoplasm
more... - cytoskeleton
- intraflagellar transport particle B
- microtubule basal body
- microtubule-based flagellum
- motile primary cilium
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|
| | |
| RMND5B | 8 |
BP MF CC |
|
| KIAA0947 | 8 |
BP MF CC |
|
| DDX24 | 8 |
BP MF CC |
|
| C1orf59 | 8 |
BP MF CC |
|
| NUB1 | 8 |
BP MF CC |
|
| MRS2 | 8 |
BP MF CC |
| | cellular_component | - integral to membrane
- membrane
- mitochondrial inner membrane
- mitochondrion
more...
|
| | |
| EIF4A1 | 8 |
BP MF CC |
| biological_process | - RNA metabolic process
- cellular protein metabolic process
- gene expression
- mRNA metabolic process
more... - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
- nuclear-transcribed mRNA poly(A) tail shortening
- organ regeneration
- translation
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| | cellular_component | - cytosol
- eukaryotic translation initiation factor 4F complex
|
| | molecular_function | - ATP binding
- ATP-dependent helicase activity
- RNA cap binding
- helicase activity
more... - hydrolase activity
- mRNA binding
- nucleic acid binding
- nucleotide binding
- protein binding
- translation factor activity, nucleic acid binding
- translation initiation factor activity
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|
| |
| CCDC150 | 8 |
BP MF CC |
|
| PLA2G15 | 8 |
BP MF CC |
| biological_process | - ceramide metabolic process
- fatty acid catabolic process
- lipid metabolic process
- phosphatidylcholine metabolic process
more...
|
| | cellular_component | - extracellular region
- lysosome
- mitochondrion
- soluble fraction
more...
|
| | molecular_function | - O-acyltransferase activity
- calcium-independent phospholipase A2 activity
- hydrolase activity
- lysophospholipase activity
more... - phospholipid binding
- transferase activity, transferring acyl groups
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| |
| AEN | 8 |
BP MF CC |
| biological_process | - DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
- apoptosis
- response to DNA damage stimulus
- response to ionizing radiation
more...
|
| | cellular_component | - intracellular
- nucleolus
- nucleoplasm
- nucleus
more...
|
| | molecular_function | - exonuclease activity
- hydrolase activity
- nucleic acid binding
|
| |
| PLEKHM1 | 8 |
BP MF CC |
| biological_process | - intracellular signal transduction
|
| | | |
| MTMR1 | 8 |
BP MF CC |
| | cellular_component | - cellular_component
- plasma membrane
|
| | molecular_function | - hydrolase activity
- phosphatase activity
- protein tyrosine phosphatase activity
|
| |
| TNK1 | 8 |
BP MF CC |
| biological_process | - negative regulation of Ras protein signal transduction
- negative regulation of cell growth
- protein autophosphorylation
- protein phosphorylation
more... - signal transduction
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| | | |
| TRIM11 | 8 |
BP MF CC |
| biological_process | - negative regulation of neurogenesis
- negative regulation of transcription, DNA-dependent
- response to virus
|
| | cellular_component | - cytoplasm
- intracellular
- nucleus
|
| | molecular_function | - ligase activity
- metal ion binding
- transcription factor binding
- ubiquitin-protein ligase activity
more... - zinc ion binding
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|
| |
| ENSA | 8 |
BP MF CC |
|
| NDRG2 | 8 |
BP MF CC |
| biological_process | - cell differentiation
- multicellular organismal development
- negative regulation of ERK1 and ERK2 cascade
- negative regulation of cytokine production
more... - negative regulation of smooth muscle cell proliferation
- nervous system development
- regulation of platelet-derived growth factor production
- regulation of vascular endothelial growth factor production
- signal transduction
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| | | molecular_function | - molecular_function
- protein binding
|
| |
| SF3B5 | 8 |
BP MF CC |
| biological_process | - RNA splicing
- gene expression
- nuclear mRNA splicing, via spliceosome
|
| | cellular_component | - U12-type spliceosomal complex
- nucleoplasm
- nucleus
|
| | |
| RAB8A | 8 |
BP MF CC |
| | | molecular_function | - GTP binding
- nucleotide binding
- protein binding
|
| |
| NUP210 | 8 |
BP MF CC |
| | | molecular_function | - protein dimerization activity
|
| |
| COPS4 | 8 |
BP MF CC |
| | cellular_component | - cytoplasm
- nucleus
- signalosome
|
| | |
| NT5DC1 | 8 |
BP MF CC |
| | | molecular_function | - hydrolase activity
- metal ion binding
|
| |
| ABCA2 | 8 |
BP MF CC |
| biological_process | - ATP catabolic process
- cholesterol homeostasis
- lipid metabolic process
- regulation of intracellular cholesterol transport
more... - regulation of transcription from RNA polymerase II promoter
- response to drug
- response to steroid hormone stimulus
- transport
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| | | molecular_function | - ATP binding
- ATPase activity
- ATPase activity, coupled to transmembrane movement of substances
- nucleotide binding
more...
|
| |
| MGRN1 | 8 |
BP MF CC |
| biological_process | - endosome to lysosome transport
- negative regulation of G-protein coupled receptor protein signaling pathway
- negative regulation of cAMP-mediated signaling
- protein monoubiquitination
more... - protein ubiquitination
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|
| | cellular_component | - cytoplasm
- cytosol
- early endosome
- nucleus
more... - plasma membrane
less...
|
| | molecular_function | - ligase activity
- metal ion binding
- protein binding
- ubiquitin-protein ligase activity
more... - zinc ion binding
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|
| |
| EIF5 | 8 |
BP MF CC |
|
| TBC1D15 | 8 |
BP MF CC |
| biological_process | - positive regulation of Rab GTPase activity
- regulation of Rab GTPase activity
|
| | cellular_component | - cytoplasm
- extracellular region
- intracellular
- mitochondrion
more...
|
| | molecular_function | - GTPase activator activity
- Rab GTPase activator activity
- protein binding
|
| |
| SLC25A23 | 8 |
BP MF CC |
| | cellular_component | - integral to membrane
- membrane
- mitochondrial inner membrane
- mitochondrion
more...
|
| | molecular_function | - binding
- calcium ion binding
|
| |
| WDR45 | 8 |
BP MF CC |
| biological_process | - autophagy
- response to starvation
|
| | | molecular_function | - phosphatidylinositol-3,5-bisphosphate binding
- small GTPase regulator activity
|
| |
| ATF4 | 8 |
BP MF CC |
| biological_process | - cellular amino acid metabolic process
- gluconeogenesis
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription, DNA-dependent
more... - regulation of transcription, DNA-dependent
- response to endoplasmic reticulum stress
- transcription from RNA polymerase II promoter
- transcription, DNA-dependent
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|
| | | |
| TSN | 8 |
BP MF CC |
| | | molecular_function | - DNA binding
- mRNA binding
- sequence-specific DNA binding
|
| |
| AKR1A1 | 8 |
BP MF CC |
| | cellular_component | - apical plasma membrane
- cytosol
|
| | molecular_function | - L-glucuronate reductase activity
- alditol:NADP+ 1-oxidoreductase activity
- electron carrier activity
- oxidoreductase activity
more...
|
| |
| TRAM2 | 8 |
BP MF CC |
| biological_process | - collagen biosynthetic process
- protein transport
|
| | cellular_component | - integral to membrane
- membrane
|
| | |
| TP53I13 | 8 |
BP MF CC |
| | cellular_component | - cytoplasm
- integral to membrane
- plasma membrane
|
| | |
| ADAM9 | 8 |
BP MF CC |
| biological_process | - PMA-inducible membrane protein ectodomain proteolysis
- activation of MAPKK activity
- cell adhesion
- cell adhesion mediated by integrin
more... - cell-cell adhesion mediated by integrin
- cell-matrix adhesion
- integrin-mediated signaling pathway
- keratinocyte differentiation
- membrane protein ectodomain proteolysis
- monocyte activation
- positive regulation of cell adhesion mediated by integrin
- positive regulation of keratinocyte migration
- positive regulation of macrophage fusion
- positive regulation of membrane protein ectodomain proteolysis
- positive regulation of protein secretion
- proteolysis
- response to calcium ion
- response to glucocorticoid stimulus
- response to hydrogen peroxide
- response to manganese ion
- response to tumor necrosis factor
- transforming growth factor beta receptor signaling pathway
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| | | molecular_function | - SH3 domain binding
- collagen binding
- integrin binding
- laminin binding
more... - metal ion binding
- metalloendopeptidase activity
- metallopeptidase activity
- peptidase activity
- protein binding
- protein kinase C binding
- zinc ion binding
less...
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| |
